Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652256 | 0.78 | RXFP1 (0.68) | MEN1KMT2ATDP1RXFP1NR1H4 | |
| SCHEMBL7083661 | 0.76 | KMT2A (0.74) | MEN1KMT2ATDP1RXFP1CA12 | |
| SCHEMBL21652187 | 0.76 | MEN1 (0.68) | MEN1KMT2ATDP1RXFP1NR1H4 | |
| SCHEMBL6830902 | 0.75 | VCP (0.41) | MEN1KMT2A | |
| SCHEMBL17376723 | 0.73 | MEN1 (0.70) | MEN1KMT2ATDP1RXFP1KCNK9 | |
| Benodanil SCHEMBL29402073 | 0.72 | MEN1 (1.00) | MEN1KMT2ATDP1RXFP1TP53 | |
| Benodanil SCHEMBL18736 | 0.72 | MEN1 (1.00) | MEN1KMT2ATDP1RXFP1TP53 | |
| SCHEMBL28084402 | 0.72 | MEN1 (0.67) | MEN1KMT2ATDP1RXFP1TP53 | |
| SCHEMBL23070511 | 0.71 | MEN1 (0.71) | MEN1KMT2ATDP1RXFP1NR1H4 | |
| SCHEMBL6826008 | 0.71 | SCN10A (0.61) | MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |