Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831033 | 1.00 | TBXAS1 (0.58) | TBXAS1MAPTTGM2KMT2AMEN1 | |
| SCHEMBL6834281 | 1.00 | TBXAS1 (0.58) | TBXAS1MAPTTGM2KMT2AMEN1 | |
| SCHEMBL6831082 | 0.90 | KMT2A (0.56) | MAPTKMT2AMEN1NPC1HSP90AA1 | |
| SCHEMBL6836014 | 0.86 | MEN1 (0.53) | MAPTKMT2AMEN1AGTR1NPC1 | |
| SCHEMBL6836012 | 0.86 | MEN1 (0.53) | MAPTKMT2AMEN1AGTR1NPC1 | |
| SCHEMBL11224523 | 0.86 | MEN1 (0.53) | MAPTKMT2AMEN1AGTR1NPC1 | |
| SCHEMBL6830998 | 0.82 | TBXAS1 (0.47) | TBXAS1MAPTTGM2KMT2AMEN1 | |
| SCHEMBL6831006 | 0.82 | TBXAS1 (0.47) | TBXAS1MAPTTGM2KMT2AMEN1 | |
| SCHEMBL6831002 | 0.82 | TBXAS1 (0.47) | TBXAS1MAPTTGM2KMT2AMEN1 | |
| SCHEMBL8775833 | 0.81 | TBXAS1 (0.61) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029928-A1 | Novel propenohydroxamic acid derivatives | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1314721-A1 | NOVEL PROPENOHYDROXAMIC ACID DERIVATIVES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029928-A1 | Novel propenohydroxamic acid derivatives | TNF, SI, HDGF | TBXAS1 33/4885MAPT 4627/4885TGM2 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.