Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553122 | 0.84 | POLB (0.56) | POLBMCOLN3ALDH1A1KDM4EHTT | |
| SCHEMBL6831347 | 0.82 | POLB (0.48) | POLBMCOLN3ALDH1A1KDM4EHTT | |
| SCHEMBL6833212 | 0.81 | ALDH1A1 (0.48) | POLBMCOLN3ALDH1A1KDM4EHTT | |
| SCHEMBL6833194 | 0.79 | KMT2A (0.39) | POLBMCOLN3ALDH1A1KDM4EKMT2A | |
| SCHEMBL6553699 | 0.73 | POLB (0.46) | POLBMCOLN3ALDH1A1KDM4EHTT | |
| SCHEMBL6553538 | 0.71 | POLB (0.44) | POLBMCOLN3ALDH1A1KMT2AMAPT | |
| SCHEMBL6832023 | 0.70 | MAPT (0.61) | POLBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6832001 | 0.70 | POLB (0.79) | POLBMCOLN3ALDH1A1KDM4EHTT | |
| SCHEMBL6831728 | 0.68 | POLB (0.74) | POLBMCOLN3ALDH1A1KDM4EHTT | |
| SCHEMBL6554657 | 0.68 | ALDH1A1 (0.43) | POLBMCOLN3ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | POLB 3871/4885MCOLN3 3672/4885ALDH1A1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.