Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24805088 | 0.85 | LMNA (0.48) | LMNAKDM5AKDM4CALDH1A1KDM4E | |
| SCHEMBL321702 | 0.82 | LMNA (0.49) | LMNAKDM5AKDM4CALDH1A1KDM4E | |
| SCHEMBL946262 | 0.81 | LMNA (0.52) | LMNAALDH1A1KDM4EPKMNPSR1 | |
| SCHEMBL1892244 | 0.81 | LMNA (0.48) | LMNAKDM5AKDM4CALDH1A1KDM4E | |
| SCHEMBL4176360 | 0.79 | LMNA (0.47) | LMNAKDM5AKDM4CALDH1A1KDM4E | |
| SCHEMBL20766461 | 0.79 | CCR8 (0.47) | LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL8634114 | 0.78 | LMNA (0.44) | LMNAKDM5AKDM4CALDH1A1KDM4E | |
| SCHEMBL10425052 | 0.78 | LMNA (0.44) | LMNAKDM5AKDM4CALDH1A1KDM4E | |
| SCHEMBL112586 | 0.78 | LMNA (0.44) | LMNAKDM5AKDM4CALDH1A1KDM4E | |
| SCHEMBL10696519 | 0.77 | LMNA (0.49) | LMNAKDM5AKDM4CALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323610-A | Pyrazolo [3,4-b ] pyridine-4-carboxamide nitrification inhibitors | 欧洲化学安特卫普公司 | 2023-06-23 | — | — | CN | claimed |
| CN-113135937-B | Fused tetracyclic compound and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-114644574-B | Dioxime ether compound and preparation method and application thereof | 湖南大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-114644574-A | Dioxime ether compound and preparation method and application thereof | 湖南大学 | 2022-06-21 | — | — | CN | disclosed |
| EP-1480999-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | Idun Pharmaceuticals (US) | 2004-12-01 | — | — | EP | disclosed |
| US-20030232788-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | IDUN PHARMACEUTICALS, INC. | 2003-12-18 | — | — | US | disclosed |
| WO-2003072528-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232788-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | DPP3, IAPP, CASP3 | LMNA 3785/4885KDM5A 2706/4885KDM4C 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.