Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13544388 | 1.00 | SLC9A1 (0.60) | SLC9A1FFAR1ALDH1A1HPGDHDAC4 | |
| SCHEMBL4210867 | 1.00 | SLC9A1 (0.60) | SLC9A1FFAR1ALDH1A1HPGDHDAC4 | |
| SCHEMBL3751420 | 1.00 | SLC9A1 (0.60) | SLC9A1FFAR1ALDH1A1HPGDHDAC4 | |
| SCHEMBL7651885 | 1.00 | SLC9A1 (0.60) | SLC9A1FFAR1ALDH1A1HPGDHDAC4 | |
| SCHEMBL805079 | 1.00 | SLC9A1 (0.60) | SLC9A1FFAR1ALDH1A1HPGDHDAC4 | |
| SCHEMBL301295 | 1.00 | SLC9A1 (0.60) | SLC9A1FFAR1ALDH1A1HPGDHDAC4 | |
| SCHEMBL3119991 | 0.89 | SLC9A1 (0.50) | SLC9A1FFAR1ALDH1A1HPGDLMNA | |
| SCHEMBL28574668 | 0.83 | FFAR1 (0.50) | SLC9A1FFAR1ALDH1A1HPGDHDAC4 | |
| SCHEMBL2835480 | 0.82 | SLC9A1 (0.68) | SLC9A1FFAR1ALDH1A1HPGDLMNA | |
| SCHEMBL6130283 | 0.82 | SLC9A1 (0.58) | SLC9A1FFAR1ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3046922-A1 | TRIAZOLOPYRIDINE ETHER DERIVATIVES AND THEIR USE IN NEUROLOGICAL AND PYSCHIATRIC DISORDERS | Bristol-Myers Squibb Company (US) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015042243-A1 | TRIAZOLOPYRIDINE ETHER DERIVATIVES AND THEIR USE IN NEUROLOGICAL AND PYSCHIATRIC DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-03-26 | — | — | WO | disclosed |
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |