Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.68 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894948 | 1.00 | SLC9A1 (0.68) | SLC9A1FAAHHTR2AHTR2CHTR2B | |
| SCHEMBL4210867 | 0.82 | SLC9A1 (0.60) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL805079 | 0.82 | SLC9A1 (0.60) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL3751420 | 0.82 | SLC9A1 (0.60) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL7651885 | 0.82 | SLC9A1 (0.60) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL301295 | 0.82 | SLC9A1 (0.60) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL6832060 | 0.82 | SLC9A1 (0.60) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL13544388 | 0.82 | SLC9A1 (0.60) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL18611059 | 0.81 | ALDH1A1 (0.67) | SLC9A1FAAHHTR2AHTR2CHTR2B | |
| SCHEMBL4069634 | 0.81 | SLC9A1 (0.68) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078337-A1 | CDK8/19 DUAL INHIBITORS AND METHODS OF USE | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078337-A1 | CDK8/19 DUAL INHIBITORS AND METHODS OF USE | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-11 | — | — | WO | disclosed |
| US-8618023-B2 | Microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2013-12-31 | — | — | US | disclosed |
| US-20100022570-A1 | NOVEL MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-01-28 | — | — | US | disclosed |
| EP-2018367-B1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-18 | — | — | EP | disclosed |
| EP-2018367-A1 | NOVEL MICROBIOCIDES | Syngeta Participations AG (CH) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007134799-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022570-A1 | NOVEL MICROBIOCIDES | QSOX1, MSR1, NOX1 | SLC9A1 452/4885FAAH 425/4885HTR2A 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.