Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650737 | 0.69 | BACE1 (0.77) | KDRCHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL18104238 | 0.68 | KDM4E (0.55) | ROCK2PIM1GSK3BAKT1AKT2 | |
| SCHEMBL9870091 | 0.67 | KDM4E (0.55) | KDRCHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL31605956 | 0.66 | BACE1 (0.40) | KDRCHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL5909487 | 0.66 | BACE1 (0.40) | KDRCHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL13820894 | 0.66 | AKT1 (0.67) | ROCK2PIM1GSK3BAKT1AKT2 | |
| SCHEMBL20019362 | 0.64 | ROCK2 (0.50) | KDRCHEK1MAP4K4CSF1RPRKACA | |
| SCHEMBL19060930 | 0.64 | KLK7 (0.65) | BACE1ROCK2PIM1GSK3BAKT1 | |
| SCHEMBL2834048 | 0.64 | GABRA1 (0.44) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL360651 | 0.64 | DYRK1A (0.74) | KDRCHEK1MAP4K4CSF1RPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004002315-A | 5,6-DIPHENYLIMIDAZO[1,2-a]PYRIMIDINE AND ITS APPLICATION | SUMITOMO CHEM CO LTD | 2004-01-08 | — | — | JP | disclosed |