Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320899 | 0.87 | CYP3A4 (0.64) | CYP3A4MAPTALOX5PTGS2MAOB | |
| SCHEMBL69301 | 0.81 | CYP3A4 (0.56) | CYP3A4MAPTALOX5PTGS2MAOB | |
| SCHEMBL684396 | 0.81 | ALOX5 (0.59) | CYP3A4MAPTALOX5PTGS2MAOB | |
| SCHEMBL29421987 | 0.79 | CYP3A4 (0.74) | CYP3A4MAPTALOX5PTGS2MAOB | |
| SCHEMBL17265618 | 0.79 | CYP3A4 (0.74) | CYP3A4MAPTALOX5PTGS2MAOB | |
| Methoxymethane SCHEMBL28032536 | 0.79 | CYP3A4 (0.54) | CYP3A4MAPTALOX5PTGS2MAOB | |
| SCHEMBL23580916 | 0.77 | ALOX5 (0.55) | CYP3A4MAPTALOX5PTGS2MAOB | |
| SCHEMBL14951058 | 0.77 | CYP3A4 (0.52) | CYP3A4MAPTALOX5PTGS2MAOB | |
| SCHEMBL7289424 | 0.77 | CYP3A4 (0.62) | CYP3A4MAPTALOX5PTGS2MAOB | |
| SCHEMBL12587137 | 0.77 | CYP3A4 (0.38) | CYP3A4MAPTALOX5PTGS2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111889-A1 | METHODS OF MAKING MULTICYCLIC COMPOUNDS USING MULTICOMPONENT/TANDEM REACTION SEQUENCES | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) | 2018-04-26 | — | — | US | disclosed |
| US-20130129832-A1 | COGNITIVE IMPAIRMENT AMELIORANT | TOHOKU UNIVERSITY (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20110287106-A1 | COGNITIVE IMPAIRMENT AMELIORANT | JAPAN ROYAL JELLEY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129832-A1 | COGNITIVE IMPAIRMENT AMELIORANT | CHAT, ACHE, PSEN1 | CYP3A4 4098/4885MAPT 7/4885ALOX5 467/4885 |
| US-20180111889-A1 | METHODS OF MAKING MULTICYCLIC COMPOUNDS USING MULTICOMPONENT/TANDEM REACTION SEQUENCES | TYMS, RTCB, POLRMT | CYP3A4 871/4885MAPT 2952/4885ALOX5 2591/4885 |
| US-20110287106-A1 | COGNITIVE IMPAIRMENT AMELIORANT | CHAT, ACHE, PSEN1 | CYP3A4 4098/4885MAPT 7/4885ALOX5 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.