Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832152 | 0.91 | GPR35 (0.38) | HSP90AB1MAPTALDH1A1GPR35HSD17B10 | |
| SCHEMBL6829455 | 0.81 | HSP90AB1 (0.41) | HSP90AB1MAPTALDH1A1GPR35HSD17B10 | |
| SCHEMBL509455 | 0.81 | RXRA (0.39) | GPR35HTTEGLN1 | |
| SCHEMBL3081523 | 0.79 | KDM4E (0.46) | HSP90AB1MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL1475954 | 0.77 | HSP90AB1 (0.43) | HSP90AB1MAPTALDH1A1GPR35HSD17B10 | |
| SCHEMBL20285289 | 0.76 | HSP90AB1 (0.34) | HSP90AB1MAPTALDH1A1HTTKDM4E | |
| SCHEMBL20278849 | 0.76 | HSP90AB1 (0.34) | HSP90AB1MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL25139321 | 0.76 | TTR (0.34) | GPR35MEN1KMT2A | |
| SCHEMBL10174520 | 0.76 | KDM4E (0.43) | HSP90AB1MAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL2154144 | 0.74 | CYP2A6 (0.41) | MAPTALDH1A1GPR35MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746990-B2 | INSECTICIDES, ACARICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-08 | — | — | US | disclosed |
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | FISCHER REINER (DE) | 2003-03-06 | — | — | US | disclosed |
| US-6358887-B1 | PREEMERGENCE, POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | CYP19A1, DDT, CYP8B1 | HSP90AB1 1084/4885MAPT 4613/4885ALDH1A1 756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.