Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948210 | 0.94 | TSHR (0.50) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL29060484 | 0.86 | PHF8 (0.46) | TSHRSLC22A6LMNAALDH1A1OR51E2 | |
| SCHEMBL28058052 | 0.86 | TSHR (0.58) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL29688998 | 0.82 | TSHR (0.54) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL27557785 | 0.82 | TSHR (0.60) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL27451286 | 0.81 | LMNA (0.58) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL6426591 | 0.81 | ALDH1A1 (0.46) | TSHRLMNAALDH1A1TDP1MEN1 | |
| SCHEMBL1289888 | 0.81 | SLC22A6 (0.65) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL19925 | 0.81 | SLC22A6 (0.65) | TSHRSLC22A6LMNANFKB1PMP22 | |
| SCHEMBL11309940 | 0.80 | TSHR (0.58) | TSHRSLC22A6LMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116042496-A | Escherichia coli genetically engineered bacterium for producing L-citrulline through fermentation, construction method and application | 河南巨龙生物工程股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-1435930-A2 | ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003032969-A2 | ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2003-04-24 | — | — | WO | disclosed |