Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.32 |
| ▸ | PYGL | P06737 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256290 | 0.84 | GHSR (0.37) | GHSRCNR1MLLT1CTSKSLC2A1 | |
| SCHEMBL6832156 | 0.81 | HDAC3 (0.42) | CTSKCTSBCTSS | |
| SCHEMBL5255075 | 0.80 | MLLT1 (0.46) | GHSRCNR1MLLT1SLC2A1ACKR3 | |
| SCHEMBL6832313 | 0.80 | MLLT1 (0.46) | GHSRCNR1MLLT1SLC2A1ACKR3 | |
| SCHEMBL6833096 | 0.80 | KMT2A (0.47) | CTSBCTSS | |
| SCHEMBL6833095 | 0.80 | PYGL (0.42) | GHSRMLLT1PYGL | |
| SCHEMBL6838954 | 0.80 | F10 (0.37) | GHSRMLLT1PYGL | |
| SCHEMBL7070887 | 0.79 | PYGL (0.42) | GHSRMLLT1PYGL | |
| SCHEMBL6840849 | 0.79 | GHSR (0.38) | GHSRCNR1MLLT1CTSKSLC2A1 | |
| SCHEMBL5256296 | 0.79 | GHSR (0.38) | GHSRCNR1MLLT1CTSKSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747053-B2 | Heteroaryl nitriles | ROCHE PALO ALTO LLC | 2004-06-08 | — | — | US | disclosed |