Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 4/20 | 0.42 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 13/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838954 | 0.93 | F10 (0.37) | PYGLMLLT1GHSROPRM1 | |
| SCHEMBL7070887 | 0.90 | PYGL (0.42) | PYGLMLLT1GHSR | |
| SCHEMBL6839074 | 0.87 | GHSR (0.41) | PYGLMLLT1GHSR | |
| SCHEMBL5254546 | 0.84 | MLLT1 (0.41) | PYGLMLLT1SRCABL1PDGFRB | |
| SCHEMBL6829592 | 0.83 | NPC1 (0.48) | PDGFRBFLT3 | |
| SCHEMBL6832689 | 0.83 | CTSK (0.38) | PYGLGHSROPRM1 | |
| SCHEMBL6832876 | 0.81 | GHSR (0.37) | PYGLGHSR | |
| SCHEMBL6833097 | 0.80 | GHSR (0.38) | PYGLMLLT1GHSR | |
| SCHEMBL5258969 | 0.79 | MLLT1 (0.53) | MLLT1SRCABL1PDGFRBKIT | |
| SCHEMBL6834814 | 0.79 | MLLT1 (0.53) | MLLT1SRCABL1PDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747053-B2 | Heteroaryl nitriles | ROCHE PALO ALTO LLC | 2004-06-08 | — | — | US | disclosed |