SCHEMBL6833199

SCHEMBL6833199

N#Cc1ccc(NC(=O)c2cc3cccc(NC(=O)C45CC6CC(CC(C6)C4)C5)c3[nH]2)c(C(=O)O)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.42
CNR2 P34972 3/20 0.41
SERPINE1 P05121 2/20 0.40
ALB P02768 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
NHERF1 O14745 1/20 0.36
NR1H4 Q96RI1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830705 0.85 ALB (0.42) RXFP1ALBKMT2AHTTNHERF1
SCHEMBL6834154 0.83 KMT2A (0.49) RXFP1SERPINE1ALBMEN1KMT2A
SCHEMBL6834472 0.83 ALB (0.43) RXFP1ALBNHERF1NR1H4
SCHEMBL6833137 0.82 MAP3K5 (0.44) RXFP1ALBKMT2ANHERF1NR1H4
SCHEMBL6862764 0.82 MEN1 (0.37) RXFP1CNR2MEN1KMT2ANPSR1
SCHEMBL6707720 0.82 MEN1 (0.36) RXFP1CNR2MEN1KMT2ANPSR1
SCHEMBL6834115 0.82 ALB (0.47) RXFP1SERPINE1ALBMEN1KMT2A
SCHEMBL6835708 0.82 CCKAR (0.51) SMN1; SMN2NPC1LMNARAB9ANHERF1
SCHEMBL6833114 0.81 ALB (0.42) RXFP1ALBLMNANHERF1NR1H4
SCHEMBL6833687 0.81 RXFP1 (0.43) RXFP1ALBLMNANHERF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US claimed
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 RXFP1 3523/4885CNR2 3495/4885SERPINE1 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.