SCHEMBL6834154

SCHEMBL6834154

N#Cc1ccc(NC(=O)c2cc3cccc(NC(=O)c4ccccc4)c3[nH]2)c(C(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
ALB P02768 1/20 0.48
NR1H4 Q96RI1 1/20 0.48
RXFP1 Q9HBX9 2/20 0.47
F2 P00734 1/20 0.46
PLG P00747 1/20 0.46
PLAU P00749 1/20 0.46
KLKB1 P03952 1/20 0.46
PRSS1 P07477 1/20 0.46
MEN1 O00255 3/20 0.46
PKM P14618 2/20 0.46
SERPINE1 P05121 1/20 0.46
LTC4S Q16873 1/20 0.46
MAPT P10636 1/20 0.45
GRIK1 P39086 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NHERF1 O14745 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
AKR1C4 P17516 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834115 0.96 ALB (0.47) KMT2AALBNR1H4RXFP1F2
SCHEMBL6834385 0.95 SERPINE1 (0.51) KMT2AALBNR1H4RXFP1SERPINE1
SCHEMBL6830877 0.93 AKR1C2 (0.48) KMT2AALBNR1H4RXFP1MEN1
SCHEMBL6830615 0.92 ALB (0.44) KMT2AALBNR1H4RXFP1MEN1
SCHEMBL6835708 0.92 CCKAR (0.51) NHERF1NPC1RAB9A
SCHEMBL6833137 0.91 MAP3K5 (0.44) KMT2AALBNR1H4RXFP1PKM
SCHEMBL6835688 0.90 GFER (0.45) ALBNR1H4RXFP1NHERF1NPC1
SCHEMBL6834504 0.88 LMNA (0.47) KMT2AALBRXFP1MEN1PKM
SCHEMBL6833897 0.88 ALB (0.42) KMT2AALBNR1H4RXFP1PKM
SCHEMBL6830151 0.88 ALB (0.42) KMT2AALBNR1H4RXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US claimed
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 KMT2A 2853/4885ALB 1417/4885NR1H4 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.