Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.70 |
| ▸ | GALR3 | O60755 | 3/20 | 0.69 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PDE6D | O43924 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | PTAFR | P25105 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969688 | 0.86 | TNF (0.70) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL15081197 | 0.83 | ALDH1A1 (0.74) | TNFRAB9ATP53LMNAHTT | |
| SCHEMBL6833621 | 0.83 | TNF (0.81) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL231295 | 0.83 | TNF (1.00) | TNFGALR3NR2F2RAB9AHDAC1 | |
| Chlormidazole SCHEMBL148113 | 0.82 | GALR3 (1.00) | TNFGALR3NR2F2RAB9AHDAC1 | |
| Chlormidazole SCHEMBL30402878 | 0.82 | GALR3 (1.00) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL9260111 | 0.81 | TNF (0.77) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL3974900 | 0.81 | TNF (0.77) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL12771519 | 0.81 | GALR3 (1.00) | TNFGALR3NR2F2RAB9AHDAC1 | |
| SCHEMBL8320197 | 0.81 | TNF (0.77) | TNFGALR3NR2F2RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6749977-B1 | PROVIDE GOOD DYE-FORMING ACTIVITY AND WHICH, AT THE SAME TIME, YIELD LITTLE OR NO INCREASED FOG AND/ OR PROVIDE LITTLE OR NO DECREASE IN DMAX AFTER STORAGE | EASTMAN KODAK COMPANY | 2004-06-15 | — | — | US | disclosed |