Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TCF4 | P15884 | 2/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927343 | 1.00 | TCF4 (0.55) | TCF4CTNNB1CYP19A1ALDH1A1HTT | |
| SCHEMBL6834369 | 0.92 | TCF4 (0.65) | TCF4CTNNB1CYP19A1ALDH1A1HTT | |
| SCHEMBL6830952 | 0.89 | TCF4 (0.61) | TCF4CTNNB1CYP19A1ALDH1A1HTT | |
| SCHEMBL6830949 | 0.89 | TCF4 (0.61) | TCF4CTNNB1CYP19A1ALDH1A1HTT | |
| SCHEMBL7163569 | 0.88 | TCF4 (0.60) | TCF4CTNNB1CYP19A1ALDH1A1HTT | |
| SCHEMBL6836008 | 0.84 | TCF4 (0.55) | TCF4CTNNB1CYP19A1ALDH1A1HTT | |
| SCHEMBL6836003 | 0.84 | TCF4 (0.55) | TCF4CTNNB1CYP19A1ALDH1A1HTT | |
| SCHEMBL6836006 | 0.84 | TCF4 (0.55) | TCF4CTNNB1CYP19A1ALDH1A1HTT | |
| SCHEMBL6830942 | 0.81 | TP53 (0.39) | ALDH1A1HTTMAPTGAAMAPK1 | |
| SCHEMBL13546155 | 0.78 | TCF4 (0.80) | TCF4CTNNB1CYP19A1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029928-A1 | Novel propenohydroxamic acid derivatives | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1314721-A1 | NOVEL PROPENOHYDROXAMIC ACID DERIVATIVES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029928-A1 | Novel propenohydroxamic acid derivatives | TNF, SI, HDGF | TCF4 2045/4885CTNNB1 1993/4885CYP19A1 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.