Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31126473 | 1.00 | ALDH1A1 (0.72) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL27672060 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL11879670 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL30810264 | 0.81 | KIF11 (0.51) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL21983781 | 0.80 | KIF11 (0.50) | ALDH1A1MAPTMEN1KMT2AKIF11 | |
| SCHEMBL5518568 | 0.78 | MEN1 (0.55) | ALDH1A1MAPTMEN1KMT2ACA12 | |
| SCHEMBL5118478 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL9723073 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL6833378 | 0.77 | POLB (0.51) | ALDH1A1MAPTKMT2APOLBNPSR1 | |
| SCHEMBL1132575 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MAPTCYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107625766-B | Application of thiazole compound as antibacterial synergist | 上海医药工业研究院 | 2021-08-31 | — | — | CN | disclosed |
| EP-1467981-A1 | 4(HETERO-) ARYL SUBSTITUTED (THIA-/OXA-/PYRA) ZOLES FOR INHIBITION OF TIE-2 | Kylix Pharmaceuticals B.V. (NL) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003062215-A1 | 4(HETERO-) ARYL SUBSTITUTED (THIA-/OXA-/PYRA) ZOLES FOR INHIBITION OF TIE-2 | KYLIX PHARMACEUTICALS B.V. (NL) | 2003-07-31 | — | — | WO | disclosed |