Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834622 | 0.85 | GRIN2B (0.77) | GRIN2BFYNBCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL10446804 | 0.83 | GRIN2B (0.74) | GRIN2BFYNBCHEACHEBACE1 | |
| SCHEMBL13357772 | 0.82 | GRIN2B (0.58) | GRIN2BFYNBCHEACHEBACE1 | |
| SCHEMBL5358070 | 0.82 | GRIN2B (0.58) | GRIN2BFYNKDM1ABCHEACHE | |
| SCHEMBL5358231 | 0.82 | GRIN2B (0.58) | GRIN2BFYNBCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL10447002 | 0.81 | GRIN2B (0.57) | GRIN2BFYNBCHEACHEBACE1 | |
| Hydrochloric Acid SCHEMBL10447191 | 0.81 | POLB (0.62) | GRIN2BFYNKDM1ABCHEACHE | |
| SCHEMBL1241255 | 0.79 | RAB9A (0.58) | GRIN2BKDM1ABCHEACHEBACE1 | |
| SCHEMBL8338757 | 0.78 | GRIN2B (0.54) | GRIN2BFYNSIGMAR1MEN1RAB9A | |
| SCHEMBL5361147 | 0.78 | KMT2A (0.60) | GRIN2BFYNKDM1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096771-A1 | BIARYL COMPOUNDS HAVING ACTIVITY AT THE 5HT5A RECEPTOR | GLAXO GROUP LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |