Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.45 |
| ▸ | CA2 | P00918 | 11/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833947 | 0.89 | AKR1C2 (0.51) | AKR1C2AKR1C1AKR1C4AKR1C3KCNK2 | |
| SCHEMBL6833153 | 0.89 | METAP2 (0.46) | AKR1C2AKR1C1AKR1C4AKR1C3METAP2 | |
| SCHEMBL6822001 | 0.88 | MEN1 (0.43) | AKR1C2AKR1C1AKR1C4AKR1C3METAP2 | |
| SCHEMBL6834200 | 0.86 | MEN1 (0.51) | AKR1C2AKR1C1AKR1C4AKR1C3METAP2 | |
| SCHEMBL6833780 | 0.85 | ALB (0.55) | ALBKDM4E | |
| SCHEMBL6833164 | 0.85 | RXFP1 (0.54) | AKR1C2AKR1C1METAP2KDM4E | |
| SCHEMBL6833802 | 0.84 | ALB (0.66) | ALBKDM4E | |
| SCHEMBL6834204 | 0.84 | KMT2A (0.51) | AKR1C2AKR1C1AKR1C4AKR1C3CA12 | |
| SCHEMBL6834329 | 0.82 | HIF1A (0.60) | AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6830124 | 0.80 | AKR1C2 (0.43) | AKR1C2AKR1C1AKR1C4AKR1C3ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | CA1 2993/4885CA2 2212/4885AKR1C2 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.