SCHEMBL6833934

SCHEMBL6833934

N#Cc1ccc(NC(=O)c2cnc(Cl)cn2)c(C(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALB P02768 2/20 0.46
F10 P00742 3/20 0.44
PYGL P06737 1/20 0.42
PYGM P11217 1/20 0.42
JUN P05412 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
TRPM4 Q8TD43 1/20 0.41
GSK3A P49840 1/20 0.41
GSK3B P49841 1/20 0.41
MAP2K1 Q02750 1/20 0.40
PPARG P37231 1/20 0.40
PRSS12 P56730 1/20 0.40
STING1 Q86WV6 1/20 0.40
SIRT6 Q8N6T7 1/20 0.40
TMPRSS4 Q9NRS4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6833057 0.84 MEN1 (0.65) KMT2AMEN1L3MBTL1ALBF10
SCHEMBL6818963 0.84 ALB (0.49) KMT2AMEN1L3MBTL1ALBF10
SCHEMBL6834161 0.84 PPARG (0.44) KMT2AMEN1ALBF10PYGL
SCHEMBL6834011 0.83 MEN1 (0.51) KMT2AMEN1ALBPYGLPYGM
SCHEMBL6834227 0.82 PTPRC (0.55) KMT2AMEN1JUNNFKB1NFKB2
SCHEMBL6835589 0.81 PYGL (0.50) KMT2AMEN1ALBF10PYGL
SCHEMBL6818218 0.80 ALB (0.45) ALBF10PYGLPYGMTRPM4
SCHEMBL6833173 0.80 PYGL (0.43) KMT2AALBF10PYGLPYGM
SCHEMBL6833170 0.80 PYGL (0.43) KMT2AALBF10PYGLPYGM
SCHEMBL6833859 0.80 GRM4 (0.61) KMT2APYGLPYGMNFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 KMT2A 2853/4885MEN1 4132/4885L3MBTL1 2096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.