Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932947 | 0.82 | POLB (0.52) | KDM4EMAPTAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6833355 | 0.78 | ABL1 (0.50) | HPGDKDM4EALDH1A1MAPTAKR1C2 | |
| SCHEMBL6926558 | 0.78 | MEN1 (0.48) | KDM4EMAPTAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6933488 | 0.76 | AKR1C2 (0.52) | KDM4EMAPTAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6350712 | 0.75 | AKR1C2 (0.63) | HPGDKDM4EALDH1A1MAPTAKR1C2 | |
| SCHEMBL6835614 | 0.75 | MEN1 (0.47) | KDM4EMAPTAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6819149 | 0.75 | AKR1C2 (0.54) | HPGDALDH1A1MAPTAKR1C2AKR1C1 | |
| SCHEMBL6834451 | 0.75 | STING1 (0.48) | ALDH1A1MAPTAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6833834 | 0.74 | MEN1 (0.47) | KDM4EALDH1A1MAPTAKR1C2AKR1C1 | |
| SCHEMBL6833251 | 0.74 | MEN1 (0.47) | KDM4EMAPTAKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | HPGD 1657/4885KDM4E 1240/4885ALDH1A1 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.