Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 9/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834019 | 0.82 | HPGD (0.52) | MAPTAKR1C2AKR1C1KDM4EAKR1C4 | |
| SCHEMBL6830598 | 0.79 | POLB (0.53) | POLBMAPTPLK1AKR1C2AKR1C1 | |
| SCHEMBL6834239 | 0.78 | POLB (0.52) | POLBPLK1AKR1C2AKR1C1TDP1 | |
| SCHEMBL6830480 | 0.78 | POLB (0.52) | POLBPLK1AKR1C2AKR1C1TDP1 | |
| SCHEMBL6833223 | 0.76 | POLB (0.52) | POLBPLK1AKR1C2AKR1C1TDP1 | |
| SCHEMBL6833242 | 0.76 | PLK1 (0.58) | POLBPLK1AKR1C2AKR1C1TDP1 | |
| SCHEMBL6819558 | 0.75 | POLB (0.51) | POLBPLK1AKR1C2AKR1C1TDP1 | |
| SCHEMBL6813815 | 0.75 | PLK1 (0.57) | POLBPLK1AKR1C2AKR1C1KDM4E | |
| SCHEMBL6833147 | 0.73 | POLB (0.53) | POLBMAPTPLK1AKR1C2AKR1C1 | |
| SCHEMBL14075210 | 0.69 | PLK1 (0.69) | POLBPLK1AKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | POLB 637/4885MAPT 4759/4885TP53 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.