Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830501 | 0.81 | KMT2A (0.76) | MAPTKDM4EKMT2AMEN1GFER | |
| SCHEMBL1307732 | 0.80 | GFER (0.76) | MAPTKDM4EAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6834682 | 0.78 | SORT1 (0.60) | MAPTAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6359676 | 0.78 | AKR1C2 (0.55) | MAPTKDM4EAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6818060 | 0.77 | AKR1C2 (0.51) | MAPTKDM4EAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL1308673 | 0.76 | AKR1C2 (0.62) | MAPTKDM4EAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL379808 | 0.76 | CYP3A4 (0.60) | MAPTKMT2AMEN1ACLYALDH1A1 | |
| SCHEMBL9513479 | 0.76 | MAPT (0.80) | MAPTAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6834036 | 0.76 | SMN1; SMN2 (0.58) | MAPTKDM4EAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL24688078 | 0.75 | RXFP1 (0.58) | MAPTKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | MAPT 4759/4885KDM4E 1240/4885AKR1C2 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.