Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25341236 | 0.76 | CHRM3 (0.63) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL30307081 | 0.75 | CHRM3 (0.61) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| SCHEMBL9295790 | 0.74 | CHRM3 (0.59) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| SCHEMBL13541547 | 0.73 | KCNH2 (0.74) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| SCHEMBL13740317 | 0.73 | CHRM3 (0.58) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| Iodide SCHEMBL6834400 | 0.72 | CHRM3 (0.55) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| SCHEMBL10524246 | 0.72 | CHRM3 (0.57) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| Isopropamide SCHEMBL100256 | 0.72 | CHRM3 (1.00) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| SCHEMBL4538265 | 0.71 | CHRM3 (0.80) | CHRM3KCNH2CHRM2CYP2D6LMNA | |
| SCHEMBL2984162 | 0.71 | CHRM3 (0.56) | CHRM3KCNH2CHRM2CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259955-A1 | New pharmaceutical compositions containing ambroxol and isopropamide iodide | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-12-23 | — | — | US | disclosed |