Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropamide SCHEMBL100256 | 0.89 | CHRM3 (1.00) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Isopropamide SCHEMBL3082703 | 0.88 | CHRM3 (0.97) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Isopropamide SCHEMBL100255 | 0.88 | KDM4E (1.00) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Isopropamide SCHEMBL14672609 | 0.87 | CHRM3 (0.94) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Isopropamide SCHEMBL7796559 | 0.82 | CHRM3 (0.85) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Isopropamide SCHEMBL17923572 | 0.78 | KDM4E (0.79) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Ambutonium SCHEMBL11946672 | 0.74 | CHRM3 (0.67) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| Ambutonium SCHEMBL249674 | 0.72 | CHRM3 (0.65) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL6834396 | 0.71 | CHRM3 (0.56) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL25341236 | 0.71 | CHRM3 (0.63) | CHRM3CHRM2KCNH2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916305-A | Multi-carrier medicament dispenser | 陆品公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-108033921-B | 3, 5-diamino-6-chloro-N- (N- (4- (4- (2- (hexyl (2,3,4,5, 6-pentahydroxyhexyl) amino) ethoxy) phenyl) butyl) carbamimidoyl) pyrazine-2-carboxamide | 帕里昂科学公司 | 2021-07-20 | — | — | CN | disclosed |
| JP-2009197011-A | ANTIRHEUMIC AGENT | DAIICHI SANKYO HEALTHCARE CO LTD | 2009-09-03 | — | — | JP | disclosed |