Isopropamide

Isopropamide

SCHEMBL100256

CC(C)[N+](C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)C(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1CHRM3

The experimentally established mechanism targets of Isopropamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 7/20 1.00
CHRM1 known ✓ P11229 1/20 1.00
CHRM2 P08172 4/20 1.00
KCNH2 Q12809 3/20 1.00
CYP2D6 P10635 2/20 1.00
LMNA P02545 1/20 1.00
KDM4E B2RXH2 1/20 0.97
CTDSP1 Q9GZU7 1/20 0.97
OPRK1 P41145 2/20 0.45
SLC22A2 O15244 1/20 0.45
SLC22A1 O15245 1/20 0.45
PGR P06401 1/20 0.45
THRB P10828 1/20 0.45
ADRB3 P13945 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
PDE3A Q14432 1/20 0.45
SLC47A1 Q96FL8 1/20 0.45
CYP3A4 P08684 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropamide SCHEMBL100255 0.98 KDM4E (1.00) CHRM3CHRM2KCNH2CYP2D6LMNA
Isopropamide SCHEMBL3082703 0.98 CHRM3 (0.97) CHRM3CHRM2KCNH2CYP2D6LMNA
Isopropamide SCHEMBL14672609 0.97 CHRM3 (0.94) CHRM3CHRM2KCNH2CYP2D6LMNA
Isopropamide SCHEMBL7796559 0.92 CHRM3 (0.85) CHRM3CHRM2KCNH2CYP2D6LMNA
SCHEMBL4538265 0.89 CHRM3 (0.80) CHRM3CHRM2KCNH2CYP2D6LMNA
Isopropamide SCHEMBL17923572 0.88 KDM4E (0.79) CHRM3CHRM2KCNH2CYP2D6LMNA
Ambutonium SCHEMBL11946672 0.80 CHRM3 (0.67) CHRM3CHRM2KCNH2CYP2D6LMNA
Ambutonium SCHEMBL249674 0.79 CHRM3 (0.65) CHRM3CHRM2KCNH2CYP2D6LMNA
SCHEMBL25341236 0.78 CHRM3 (0.63) CHRM3CHRM2KCNH2CYP2D6LMNA
Hydrochloric Acid SCHEMBL30307081 0.76 CHRM3 (0.61) CHRM3CHRM2KCNH2CYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3995 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
US-20250302814-A1 METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA APNIMED, INC. (DELAWARE) 2025-10-02 US claimed
EP-4154879-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NICOTINE WITHDRAWAL SYMPTOMS KOREA INST SCI & TECH (KR) 2025-09-10 EP claimed
US-20250241933-A1 METHODS OF TREATING SLEEP APNEA WITH A COMBINATION OF A CANNABINOID AND A CARBONIC ANHYDRASE INHIBITOR APNIMED, INC. (DELAWARE) 2025-07-31 US claimed
WO-2025137591-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR PROMOTING ZINC SOLUBILIZATION AND ZINC UPTAKE IN PLANTS Tenfold Technologies, LLC (US) 2025-06-26 WO claimed
CN-120076713-A Stable oil dispersions 安道麦阿甘有限公司 2025-05-30 CN claimed
EP-4543431-A1 METHODS OF TREATING SLEEP APNEA WITH A COMBINATION OF A CANNABINOID AND A CARBONIC ANHYDRASE INHIBITOR APNIMED, INC. (DELAWARE) (US) 2025-04-30 EP claimed
CN-119677410-A Herbicidal compositions comprising azine compounds 巴斯夫欧洲公司 2025-03-21 CN claimed
US-20240358709-A1 METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA APNIMED, INC. (DELAWARE) 2024-10-31 US claimed
CN-118785929-A Three-dimensional biocompatible matrix and application thereof in wound treatment 阿克森诺尔生命科学股份公司 2024-10-15 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
CN-1227597-A Cleaning compositions PROCTER & GAMBLE (US) 1999-09-01 CN claimed
CN-1227592-A Cleaning compositions PROCTER & GAMBLE (US) 1999-09-01 CN claimed
CN-1227591-A Cleaning compositions PROCTER & GAMBLE (US) 1999-09-01 CN claimed
US-5779661-A Method of treating dysfunctional bladder syndromes by electromotive drug administration PHYSION, S.R.L. (IT) 1998-07-14 US claimed
EP-0721348-A1 MONOGLYCERIDE/LACTATE ESTER PERMEATION ENHANCER ALZA CORPORATION (US) 1996-07-17 EP claimed
WO-1995009006-A1 MONOGLYCERIDE/LACTATE ESTER PERMEATION ENHANCER ALZA CORPORATION (US) 1995-04-06 WO claimed
US-5023088-A Drug delivery dispenser ALZA CORPORATION (US) 1991-06-11 US claimed
US-4824676-A ANTICHOLINERGIC AGENT TO SUPPRESS PERSPIRATION SCHERING CORPORATION (US) 1989-04-25 US claimed