SCHEMBL6834834

SCHEMBL6834834

O=C1C=CC(O)=C(O)C1c1cccs1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
GAA P10253 3/20 0.41
POLB P06746 1/20 0.41
ALDH1A1 P00352 8/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 6/20 0.34
HPGD P15428 3/20 0.34
TDP1 Q9NUW8 2/20 0.33
ALOX15 P16050 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
GLA P06280 1/20 0.33
CRHBP P24387 1/20 0.33
MAPK1 P28482 1/20 0.33
CRHR2 Q13324 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 1/20 0.33
HSD17B10 Q99714 4/20 0.32
CASP1 P29466 2/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6839599 0.69 ALDH1A1 (0.56) MAPTGAAPOLBALDH1A1MEN1
SCHEMBL6839433 0.68 MAPT (0.43) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28764002 0.67 ALDH1A1 (0.39) MAPTPOLBALDH1A1MEN1KMT2A
SCHEMBL31462136 0.66 ALDH1A1 (0.44) MAPTGAAPOLBALDH1A1MEN1
SCHEMBL6838726 0.66 KDM4E (0.41) MAPTGAAPOLBALDH1A1MEN1
SCHEMBL8083470 0.64 ALDH1A1 (0.40) MAPTGAAPOLBALDH1A1MEN1
SCHEMBL15621465 0.63 POLB (0.57) MAPTGAAPOLBALDH1A1MEN1
SCHEMBL6841322 0.63 ESR1 (0.40) ALDH1A1KDM4EHSD17B10
SCHEMBL10490942 0.63 MAPT (0.46) MAPTGAAPOLBALDH1A1MEN1
SCHEMBL24516518 0.63 ALDH1A1 (0.42) MAPTGAAPOLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6759367-B2 COMPRISING THERMOSENSITIVE ELEMENT AND SUPPORT, THE THERMOSENSITIVE ELEMENT CONTAINING A SUBSTANTIALLY LIGHT-INSENSITIVE ORGANIC SILVER SALT, A 3,4-DIHYDROXYBENZENE COMPOUND, A BINDER AGFA-GEVAERT (BE) 2004-07-06 US disclosed