Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839521 | 0.80 | CYP2A6 (0.41) | MAPTRAB9AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL6839599 | 0.75 | ALDH1A1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2DDB1 | |
| SCHEMBL6834834 | 0.68 | MAPT (0.41) | MAPTTP53KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL6838726 | 0.64 | KDM4E (0.41) | MAPTNPC1SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL31549514 | 0.62 | — | — | |
| SCHEMBL30622715 | 0.61 | MAPT (0.50) | MAPTNPC1TP53RAB9AMAPK10 | |
| SCHEMBL15621216 | 0.61 | MAPT (0.70) | MAPTNPC1TP53RAB9AMAPK10 | |
| SCHEMBL855370 | 0.60 | RAB9A (1.00) | MAPTNPC1TP53RAB9AMAPK10 | |
| SCHEMBL22732802 | 0.59 | MAPT (0.46) | MAPTNPC1TP53RAB9AMAPK10 | |
| SCHEMBL4309904 | 0.57 | MAPT (0.50) | MAPTNPC1TP53RAB9AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759367-B2 | COMPRISING THERMOSENSITIVE ELEMENT AND SUPPORT, THE THERMOSENSITIVE ELEMENT CONTAINING A SUBSTANTIALLY LIGHT-INSENSITIVE ORGANIC SILVER SALT, A 3,4-DIHYDROXYBENZENE COMPOUND, A BINDER | AGFA-GEVAERT (BE) | 2004-07-06 | — | — | US | disclosed |