Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834894 | 1.00 | ABCB1 (0.38) | ABCB1CYP2D6THRBHSD17B10 | |
| SCHEMBL9744786 | 0.87 | ABCB1 (0.40) | ABCB1CYP2D6THRBHSD17B10 | |
| SCHEMBL9744999 | 0.87 | ABCB1 (0.40) | ABCB1CYP2D6THRBHSD17B10 | |
| SCHEMBL9744773 | 0.87 | ABCB1 (0.40) | ABCB1CYP2D6THRBHSD17B10 | |
| SCHEMBL21694329 | 0.86 | ABCB1 (0.38) | ABCB1CYP2D6THRBHSD17B10 | |
| SCHEMBL4618909 | 0.81 | ABCB1 (0.37) | ABCB1 | |
| SCHEMBL16373895 | 0.81 | ABCB1 (0.35) | ABCB1 | |
| SCHEMBL4618913 | 0.81 | ABCB1 (0.37) | ABCB1 | |
| SCHEMBL6839082 | 0.79 | ABCB1 (0.49) | ABCB1CYP2D6THRBHSD17B10 | |
| SCHEMBL21694355 | 0.79 | ABCB1 (0.49) | ABCB1CYP2D6THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10780105-B2 | Substituted nucleosides, nucleotides and analogs thereof | Janssen Biopharma, Inc. (US) | 2020-09-22 | — | — | US | disclosed |
| US-20190054108-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen Pharmaceuticals, Inc. | 2019-02-21 | — | — | US | disclosed |
| WO-2015200219-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015200205-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| US-20040229840-A1 | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase | ISIS PHARMACEUTICALS, INC. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190054108-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NUDT1, NT5C3B | ABCB1 689/4885CYP2D6 3004/4885THRB 2519/4885 |
| US-20040229840-A1 | Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase | NSUN2, NSUN3, POLRMT | ABCB1 592/4885CYP2D6 2332/4885THRB 4665/4885 |
| US-10780105-B2 | Substituted nucleosides, nucleotides and analogs thereof | PNP, NUDT1, NT5C3B | ABCB1 689/4885CYP2D6 3004/4885THRB 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.