Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834973 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL15101930 | 0.88 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL432664 | 0.88 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL432665 | 0.88 | ALDH1A1 (0.39) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL7748846 | 0.82 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL1723753 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL27978258 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL10500043 | 0.78 | ALOX15 (0.35) | ALDH1A1TSHR | |
| SCHEMBL29272040 | 0.78 | HSD17B10 (0.50) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL2383130 | 0.78 | ALOX15 (0.35) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106808-A1 | Processes for preparing calanolide a and intermediates thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2004-06-03 | — | — | US | disclosed |
| EP-1352907-A1 | PROCESSES FOR PREPARING CALANOLIDE A AND INTERMEDIATES THEREOF | KURARAY CO., LTD. (JP) | 2003-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106808-A1 | Processes for preparing calanolide a and intermediates thereof | CALR, CYP51A1, CYP4A11 | ALDH1A1 1043/4885TSHR 3981/4885HSD17B10 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.