SCHEMBL6834973

SCHEMBL6834973

CC=C(C)C(=O)OC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834972 1.00 ALDH1A1 (0.50) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL15101930 0.88 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL432664 0.88 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL432665 0.88 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL7748846 0.82 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL1723753 0.80 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL27978258 0.80 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL10500043 0.78 ALOX15 (0.35) ALDH1A1TSHR
SCHEMBL29272040 0.78 HSD17B10 (0.50) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL2383130 0.78 ALOX15 (0.35) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296906-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-09-25 US disclosed
EP-4577517-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-07-02 EP disclosed
EP-4577516-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-07-02 EP disclosed
CN-119744258-A Process for the preparation of 4-hydroxy-2-methylene-butyraldehyde, 4-hydroxy-2-methyl-but-2-enal and their esters 巴斯夫欧洲公司 2025-04-01 CN disclosed
CN-119744259-A Process for the preparation of 4-hydroxy-2-methylene-butyraldehyde, 4-hydroxy-2-methyl-but-2-enal and their esters 巴斯夫欧洲公司 2025-04-01 CN disclosed
WO-2024042131-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2024-02-29 WO disclosed
WO-2024042132-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2024-02-29 WO disclosed
CN-103201250-A Novel carboxylic acid ester compound and production therefor, and perfume composition thereof MITSUBISHI GAS CHEMICAL CO 2013-07-10 CN disclosed
CN-101213280-B Perfume composition KAO CORP 2011-05-18 CN disclosed
CN-101213280-A Perfume composition KAO CORP (JP) 2008-07-02 CN disclosed
CN-1562998-A Method for synthesizing compound in condensed carbonyl group BAIHUA PERFUME CO LTD GUANGZHO (CN) 2005-01-12 CN disclosed
CN-1184221-C New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method INST OF MEDICINAL BIOLOG TECHN (CN) 2005-01-12 CN disclosed
CN-1535284-A Method for producing polymer compositions, polymer compositions obtained by using this method, and use thereof 2004-10-06 CN disclosed
US-20040106808-A1 Processes for preparing calanolide a and intermediates thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 2004-06-03 US disclosed
EP-1352907-A1 PROCESSES FOR PREPARING CALANOLIDE A AND INTERMEDIATES THEREOF KURARAY CO., LTD. (JP) 2003-10-15 EP disclosed
CN-1400209-A New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method INST OF MEDICINAL BIOLOG TECHN (CN) 2003-03-05 CN disclosed
US-20030032736-A1 Acrylic adhesive compositions containing ketonyl (meth)acrylate KNEAFSEY BRENDAN J (IE) 2003-02-13 US disclosed
WO-2001051576-A1 ACRYLIC ADHESIVE COMPOSITIONS CONTAINING KETONYL (METH)ACRYLATE LOCTITE (R & D) LIMITED (IE) 2001-07-19 WO disclosed
US-5800907-A Method of producing lens method of fabricating article with lens articles with lens resin composition for forming defining lines and lens-forming resin composition GRAPAC JAPAN CO., INC. (JP) 1998-09-01 US disclosed
US-4009202-A 2(OR 3)-METHYL-1-ACETOXY-4-ALKOXY (OR PHENOXY)-1,3-BUTADIENES BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040106808-A1 Processes for preparing calanolide a and intermediates thereof CALR, CYP51A1, CYP4A11 ALDH1A1 1043/4885TSHR 3981/4885HSD17B10 279/4885
US-20250296906-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF ALDH1A2, ADH4, RBP4 ALDH1A1 21/4885TSHR 3564/4885HSD17B10 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.