Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705362 | 0.89 | PTPN1 (0.41) | ELANEHSP90AA1TDP2NSD2PAX8 | |
| SCHEMBL3692462 | 0.84 | PTPN1 (0.41) | ELANEHSP90AA1TDP2NSD2PAX8 | |
| SCHEMBL5843487 | 0.83 | ALDH1A1 (0.37) | ELANEHSP90AA1EPHX2PTPN1ALDH1A1 | |
| SCHEMBL6939858 | 0.79 | ALDH1A1 (0.37) | ELANEHSP90AA1EPHX2PTPN1NPC1 | |
| SCHEMBL3689674 | 0.76 | TDP2 (0.44) | ELANEHSP90AA1TDP2NSD2PAX8 | |
| SCHEMBL3699504 | 0.75 | PTPN1 (0.48) | ELANEHSP90AA1PTPN1ALDH1A1CYP1A2 | |
| SCHEMBL3700187 | 0.74 | CA2 (0.43) | PTPN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3698561 | 0.73 | TDP2 (0.44) | ELANEHSP90AA1TDP2NSD2PAX8 | |
| SCHEMBL3692504 | 0.71 | TDP2 (0.39) | ELANEHSP90AA1TDP2NSD2PAX8 | |
| SCHEMBL3690041 | 0.71 | PTPN1 (0.42) | ELANEEPHX2PTPN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152080-A1 | Method for detecting cytosine methylations | QIAGEN GMBH (DE) | 2004-08-05 | — | — | US | disclosed |