Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835176 | 0.93 | NPY5R (0.51) | NPY5RKDM4EL3MBTL1TUBB4ATUBB | |
| SCHEMBL6831681 | 0.83 | NPY5R (0.52) | NPY5RKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL6835218 | 0.82 | NPY5R (0.55) | NPY5RCYP3A4CYP2C9CYP19A1CYP11B2 | |
| SCHEMBL6836913 | 0.78 | NPY5R (0.55) | NPY5RNPC1RAB9ASIGMAR1 | |
| SCHEMBL6834506 | 0.75 | NPY5R (0.48) | NPY5RTYMSKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL6831686 | 0.73 | KDM4E (0.48) | NPY5RMAOBKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL4741122 | 0.69 | TYMS (0.55) | NPY5RTYMSMAOBKDM4EL3MBTL1 | |
| SCHEMBL12325961 | 0.69 | KDM4E (0.62) | KDM4EL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4741749 | 0.68 | NPY5R (0.50) | NPY5RTYMSMAOBKDM4EL3MBTL1 | |
| SCHEMBL2340188 | 0.66 | ALDH1A1 (0.62) | NPY5RALDH1A1MAPK14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | H1-0, H1-5, H1-3 | NPY5R 983/4885TYMS 2205/4885MAOB 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.