Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835460 | 1.00 | PARP1 (0.44) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL29446042 | 0.81 | MAOA (0.53) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL769238 | 0.81 | MAOA (0.53) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL4017169 | 0.78 | PARP1 (0.53) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL5469185 | 0.77 | L3MBTL1 (0.53) | PARP1PARP10SRD5A1NPC1RAB9A | |
| SCHEMBL9039944 | 0.77 | MAOA (0.63) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL19754402 | 0.77 | L3MBTL1 (0.53) | PARP1PARP10SRD5A1NPC1RAB9A | |
| SCHEMBL5469183 | 0.77 | L3MBTL1 (0.53) | PARP1PARP10SRD5A1NPC1RAB9A | |
| SCHEMBL9039952 | 0.77 | MAOA (0.63) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL6340362 | 0.73 | HPGD (0.58) | PARP1PARP10SRD5A1NPY5RCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110844-A1 | MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF | ASTRAZENECA AB (SE) | 2009-09-11 | — | — | WO | disclosed |
| US-20040202495-A1 | Imaging apparatus, and toner and process cartridge used in the imaging apparatus | RICOH COMPANY, LTD. (JP) | 2004-10-14 | — | — | US | disclosed |
| US-20040198791-A1 | Fused imidazole derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198791-A1 | Fused imidazole derivative | H1-0, H1-5, H1-3 | PARP1 3046/4885PARP10 3401/4885MAOA 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.