Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065084 | 0.86 | GRM5 (0.49) | NOTUMCHRM4MGLL | |
| SCHEMBL4930885 | 0.84 | STS (0.47) | NOTUMGPR119USP30 | |
| SCHEMBL14026929 | 0.84 | GPR119 (0.46) | GPR119USP30 | |
| SCHEMBL21360375 | 0.84 | GPR119 (0.55) | GPR119USP30 | |
| SCHEMBL8236255 | 0.84 | GPR119 (0.55) | GPR119USP30 | |
| SCHEMBL14026913 | 0.84 | USP30 (0.53) | GPR119USP30 | |
| SCHEMBL3609661 | 0.82 | USP30 (0.58) | NOTUMGPR119USP30CHRM4MGLL | |
| SCHEMBL688078 | 0.81 | GPR119 (0.56) | NOTUMGPR119CHRM4MGLLEGLN2 | |
| SCHEMBL18452908 | 0.79 | HRH3 (0.48) | NOTUMGPR119USP30 | |
| SCHEMBL20510393 | 0.78 | GPR119 (0.50) | NOTUMGPR119USP30CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1496361-A | Phenyl derivatives 3 | Ĭ��ר���ɷ�����˾ | 2004-05-12 | — | — | CN | disclosed |
| US-20040082563-A1 | Phenyl derivatives 3 | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1368341-A1 | PHENYL DERIVATIVES 3 | MERCK PATENT GmbH (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002074765-A1 | PHENYL DERIVATIVES 3 | MERCK PATENT GMBH (DE) | 2002-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082563-A1 | Phenyl derivatives 3 | F2, F11, F12 | NOTUM 3173/4885GPR119 2646/4885USP30 3843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.