Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146728 | 0.82 | ADORA2B (1.00) | ADORA2BADORA2AMAOBHTTHPGD | |
| SCHEMBL10616168 | 0.78 | ADORA2B (0.72) | ADORA2BADORA2AMAOBHTTHPGD | |
| SCHEMBL515794 | 0.77 | ADORA2B (0.74) | ADORA2BADORA2AMAOBHTTHPGD | |
| SCHEMBL515900 | 0.76 | ADORA2B (0.72) | ADORA2BADORA2AMAOBHTTHPGD | |
| SCHEMBL17626266 | 0.75 | ADORA2B (0.67) | ADORA2BADORA2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL14129137 | 0.75 | ADORA2B (1.00) | ADORA2BADORA2AMAOBHPGDKDM4E | |
| SCHEMBL7030152 | 0.75 | ADORA2B (0.70) | ADORA2BADORA2AHTTHPGDSMN1; SMN2 | |
| SCHEMBL683962 | 0.73 | ADORA2B (0.62) | ADORA2BADORA2AMAOBHTTHPGD | |
| SCHEMBL8318291 | 0.72 | ADORA2B (0.58) | ADORA2BADORA2AMAOBHTTHPGD | |
| Hydrochloric Acid SCHEMBL11388923 | 0.72 | ADORA2B (0.61) | ADORA2BADORA2AMAOBHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058170-A9 | METHODS FOR TREATING MALARIA BY MODULATION OF G PROTEIN FUNCTION | UNIV NORTHWESTERN (US) | 2004-08-19 | — | — | WO | disclosed |
| WO-2004058170-A2 | METHODS FOR TREATING MALARIA BY MODULATION OF G PROTEIN FUNCTION | NORTHWESTERN UNIVERSITY (US) | 2004-07-15 | — | — | WO | disclosed |
| US-5658889-A | ADMINISTERING 5-AMINO-4-IMIDAZLECARBOXAMIDE RIBOSIDE WHICH BINDS ADENOSINE MONOPHOSPHATE SITE OF FRUCTOSE-1,6-DIPHOSPHATASE | GENSIA PHARMACEUTICALS, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0427799-B1 | METHOD AND COMPOUNDS FOR AICA RIBOSIDE DELIVERY AND FOR LOWERING BLOOD GLUCOSE | GENSIA PHARMA (US) | 1994-11-30 | — | — | EP | disclosed |
| EP-0427799-A4 | METHOD AND COMPOUNDS FOR AICA RIBOSIDE DELIVERY AND FOR LOWERING BLOOD GLUCOSE | — | 1991-07-24 | — | — | EP | disclosed |
| EP-0427799-A1 | METHOD AND COMPOUNDS FOR AICA RIBOSIDE DELIVERY AND FOR LOWERING BLOOD GLUCOSE. | GENSIA PHARMA (US) | 1991-05-22 | — | — | EP | disclosed |
| WO-1990009163-A2 | METHOD AND COMPOUNDS FOR AICA RIBOSIDE DELIVERY AND FOR LOWERING BLOOD GLUCOSE | GENSIA PHARMACEUTICALS, INC. (US) | 1990-08-23 | — | — | WO | disclosed |