Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593295 | 0.73 | ESR1 (1.00) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL26946 | 0.73 | ESR1 (1.00) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL27726697 | 0.73 | UGT2B7 (0.50) | HIF1ATSHRADORA2ACYP3A4CYP1A2 | |
| SCHEMBL901201 | 0.73 | ESR1 (0.76) | ESR1ESR2PDCD1CD274TAAR1 | |
| Ammonia Solution, Strong SCHEMBL7989093 | 0.71 | ESR1 (0.94) | ESR1ESR2PDCD1CD274TAAR1 | |
| Methane SCHEMBL21952131 | 0.71 | ESR1 (0.94) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL3264497 | 0.68 | ESR1 (0.84) | ESR1ESR2PDCD1CD274ALOX15 | |
| SCHEMBL15232906 | 0.68 | ESR1 (0.84) | ESR1ESR2PDCD1CD274TAAR1 | |
| SCHEMBL21632799 | 0.68 | ESR1 (0.84) | ESR1ESR2PDCD1CD274HIF1A | |
| SCHEMBL9808121 | 0.68 | ESR1 (0.84) | ESR1ESR2PDCD1CD274TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753363-B1 | BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY | POLYPLASTICS CO., LTD. (JP) | 2004-06-22 | — | — | US | disclosed |