Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611251 | 0.95 | GNAI3 (0.49) | GNAI3GNAO1GNAI1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7585696 | 0.89 | GNAI3 (0.44) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL8259120 | 0.86 | HPGD (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL30839344 | 0.85 | MEN1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL16607366 | 0.85 | MEN1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA | |
| SCHEMBL13713449 | 0.84 | GNAI3 (0.54) | GNAI3GNAO1GNAI1HRH2HRH1 | |
| SCHEMBL6992740 | 0.83 | SMYD3 (0.44) | GNAI3GNAO1GNAI1KMT2AALDH1A1 | |
| SCHEMBL7421244 | 0.83 | S1PR5 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL12842703 | 0.83 | ALDH1A1 (0.38) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL8169180 | 0.82 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020261-A2 | SELECTED CGRP ANTAGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-22 | — | — | WO | disclosed |
| US-20040087622-A1 | Benzamide derivative and medicament containing the same | KATO HIDEO (JP) | 2004-05-06 | — | — | US | disclosed |
| CN-1126738-C | Benzamide derivatives and drugs containing the same | HOKURIKU PHARMACEUTICAL (JP) | 2003-11-05 | — | — | CN | disclosed |
| US-6638951-B1 | Medicament has excellent enhancing action on gastrointestinal tract motility, and is orally available with reduced side effects, the agent for therapeutic treatment of digestive diseases, an agent for improving function of gastrointestinal | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1149832-B1 | BENZAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU PHARMACEUTICAL (JP) | 2003-01-02 | — | — | EP | disclosed |
| CN-1339026-A | Benzamide derivatives and drugs containing the same | HOKURIKU PHARMACEUTICAL (JP) | 2002-03-06 | — | — | CN | disclosed |
| EP-1149832-A1 | BENZAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087622-A1 | Benzamide derivative and medicament containing the same | SLC10A2, FABP2, HDAC6 | GNAI3 938/4885GNAO1 921/4885GNAI1 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.