SCHEMBL6836154

SCHEMBL6836154

Nc1ccc(N(c2ccc(N)cc2)c2ccc(O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.68
CYP3A4 P08684 6/20 0.68
ALOX15 P16050 3/20 0.68
CA3 P07451 2/20 0.68
HIF1A Q16665 2/20 0.68
HSD17B10 Q99714 2/20 0.68
CA14 Q9ULX7 2/20 0.68
THRB P10828 2/20 0.68
CA6 P23280 1/20 0.68
CASP1 P29466 1/20 0.68
TDP1 Q9NUW8 5/20 0.61
MAPT P10636 4/20 0.61
KDM4E B2RXH2 4/20 0.61
L3MBTL1 Q9Y468 3/20 0.61
CYP2C19 P33261 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
APP P05067 4/20 0.52
MAPK1 P28482 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279529 0.86 ALOX15 (0.57) ALDH1A1CYP3A4ALOX15CA3HIF1A
SCHEMBL308803 0.86 TDP1 (0.78) ALDH1A1CYP3A4ALOX15CA3HIF1A
SCHEMBL2009254 0.86 TDP1 (0.78) ALDH1A1CYP3A4ALOX15CA3HIF1A
SCHEMBL15888471 0.84 CYP3A4 (0.48) ALDH1A1CYP3A4ALOX15CA3HIF1A
Hydrochloric Acid SCHEMBL31558767 0.83 CYP3A4 (0.74) ALDH1A1CYP3A4ALOX15CA3HIF1A
Hydrochloric Acid SCHEMBL9238428 0.83 CYP3A4 (0.74) ALDH1A1CYP3A4ALOX15CA3HIF1A
SCHEMBL30901051 0.83 TDP1 (0.74) ALDH1A1CYP3A4ALOX15CA3HIF1A
4-Aminophenol SCHEMBL6753971 0.83 ALDH1A1 (1.00) ALDH1A1CYP3A4ALOX15CA3HIF1A
4-Aminophenol SCHEMBL4861305 0.83 ALDH1A1 (1.00) ALDH1A1CYP3A4ALOX15CA3HIF1A
4-Aminophenol SCHEMBL3424 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111592669-A Multi-crosslinked carbon nanotube grafted polyimide heat-conducting film and preparation method and application thereof 吉林大学 2020-08-28 CN claimed
CN-111592669-B Multi-crosslinked carbon nanotube grafted polyimide heat-conducting film and preparation method and application thereof 吉林大学 2021-08-31 CN disclosed
US-10981865-B2 Substituted or unsubstituted allyl group-containing maleimide compound, production method therefor, and composition and cured product using said compound DIC CORPORATION (JP) 2021-04-20 US disclosed
US-20200325101-A1 SUBSTITUTED OR UNSUBSTITUTED ALLYL GROUP-CONTAINING MALEIMIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION AND CURED PRODUCT USING SAID COMPOUND DIC CORPORATION (JP) 2020-10-15 US disclosed
CN-111592669-A Multi-crosslinked carbon nanotube grafted polyimide heat-conducting film and preparation method and application thereof 吉林大学 2020-08-28 CN disclosed
US-20200109276-A1 COMPOSITION, CURED PRODUCT AND LAMINATE DIC CORPORATION (JP) 2020-04-09 US disclosed
EP-3560968-A1 COMPOSITION, CURED PRODUCT AND LAMINATE DIC Corporation (JP) 2019-10-30 EP disclosed
EP-3466925-A1 SUBSTITUTED OR UNSUBSTITUTED ALLYL GROUP-CONTAINING MALEIMIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION AND CURED PRODUCT USING SAID COMPOUND DIC Corporation (JP) 2019-04-10 EP disclosed
EP-2557106-B1 PHOTOCROSSLINKING POLYIMIDE POLYMER, A PRODUCTION METHOD FOR THE SAME AND A MEMORY ELEMENT USING THE SAME POSTECH ACADEMY-INDUSTRY FOUND (KR) 2017-05-17 EP disclosed
US-8981353-B2 Photocrosslinkable polyimide polymer, manufacturing methods for the same memory devices using the same POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-03-17 US disclosed
US-8981353-B2 Photocrosslinkable polyimide polymer, manufacturing methods for the same memory devices using the same POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-03-17 US disclosed
US-20130140532-A1 PHOTOCROSSLINKABLE POLYIMIDE POLYMER, MANUFACTURING METHODS FOR THE SAME AND MEMORY DEVICES USING THE SAME POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-06-06 US disclosed
US-20130140532-A1 PHOTOCROSSLINKABLE POLYIMIDE POLYMER, MANUFACTURING METHODS FOR THE SAME AND MEMORY DEVICES USING THE SAME POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-06-06 US disclosed
EP-2557106-A2 PHOTOCROSSLINKING POLYIMIDE POLYMER, A PRODUCTION METHOD FOR THE SAME AND A MEMORY ELEMENT USING THE SAME Postech Academy-industry Foundation (KR) 2013-02-13 EP disclosed
US-6749927-B2 CURED RESINS OF COMPOSITION OF INVENTION HAVE LOW DIELECTRIC CONSTANT, AND ARE THEREFORE PARTICULARLY SUITABLE FOR USE AS INTERLAYER DIELECTRIC IN MULTILAYER CIRCUIT BOARDS SUCH AS MULTI- CHIP MODULE-LAMINATE/DEPOSITED BOARDS FUJITSU LIMITED (JP) 2004-06-15 US disclosed
US-20020131247-A1 Dielectric resin composition and multilayer circuit board comprising dielectric layers formed therefrom FUJITSU LIMITED (JP) 2002-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10981865-B2 Substituted or unsubstituted allyl group-containing maleimide compound, production method therefor, and composition and cured product using said compound BMI1, WEE1, WEE2 ALDH1A1 1524/4885CYP3A4 364/4885ALOX15 909/4885
US-20200325101-A1 SUBSTITUTED OR UNSUBSTITUTED ALLYL GROUP-CONTAINING MALEIMIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND COMPOSITION AND CURED PRODUCT USING SAID COMPOUND BMI1, WEE1, WEE2 ALDH1A1 1524/4885CYP3A4 364/4885ALOX15 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.