SCHEMBL6836396

SCHEMBL6836396

COc1ccc2oc(=O)c(C(=O)c3cc4c(OC)cc(OC)cc4oc3=O)cc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.63
ALDH1A1 P00352 6/20 0.63
HPGD P15428 3/20 0.63
CA12 O43570 1/20 0.63
CA1 P00915 1/20 0.63
CA2 P00918 1/20 0.63
CA3 P07451 1/20 0.63
CA6 P23280 1/20 0.63
CA5A P35218 1/20 0.63
CA7 P43166 1/20 0.63
CA9 Q16790 1/20 0.63
CA14 Q9ULX7 1/20 0.63
CA5B Q9Y2D0 1/20 0.63
GAA P10253 3/20 0.59
MAOB P27338 6/20 0.57
MAPT P10636 2/20 0.55
GLA P06280 1/20 0.55
MAOA P21397 1/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6836388 0.92 ALDH1A1 (0.65) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL29436270 0.89 ALDH1A1 (0.55) KDM4EALDH1A1HPGDCA12CA1
SCHEMBL556704 0.89 ALDH1A1 (0.55) KDM4EALDH1A1HPGDCA12CA1
SCHEMBL4567092 0.88 NPC1 (0.59) KDM4EALDH1A1HPGDCA12CA1
SCHEMBL2032914 0.87 KDM4E (0.81) KDM4EALDH1A1HPGDCA12CA1
SCHEMBL2992219 0.84 MEN1 (0.59) KDM4EALDH1A1HPGDCA12CA1
SCHEMBL5940595 0.84 MEN1 (0.56) KDM4EALDH1A1HPGDCA12CA2
SCHEMBL20711137 0.83 CNR2 (0.55) KDM4EALDH1A1HPGDGAAMAOB
SCHEMBL51844 0.81 MEN1 (0.50) KDM4EALDH1A1HPGDGAAMAOB
SCHEMBL52178 0.81 ALDH1A1 (0.66) KDM4EALDH1A1HPGDMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
US-20040198859-A1 Photopolymerization systems and their use NGUYEN CHAU K (US) 2004-10-07 US disclosed
EP-0795790-B1 Peel-developable lithographic printing plate KODAK POLYCHROME GRAPHICS LLC (US) 2002-09-25 EP disclosed
EP-0730201-B1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2001-05-09 EP disclosed
US-5942372-A COMPRISED A SPECTRAL SENSITIZER THAT SENSITIZES IN THE ULTRAVIOLET OR VISIBLE REGIONS OF THE SPECTRUM AND AN N-ARYL POLYCARBOXYLIC ACID CO-INITIATOR; VERY HIGH PHOTOSPEED AND VERY GOOD SHELF-LIFE IN COMPUTER-TO-PLATE SYSTEMS KODAK POLYCHROME GRAPHICS, LLC (US) 1999-08-24 US disclosed
US-5914215-A ELEMENT COMPRISING SUPPORT HAVING PHOTOIMAGEABLE, RADIATION SENSITIVE LAYER COMPRISING UNSATURATED COMPOUND, PHOTOINITIATOR SYSTEM COMPRISING SENSITIZER SENSITIZING IN ULTRAVIOLET OR VISIBLE REGION OF SPECTRUM, CO-INITIATOR KODAK POLYCHROME GRAPHIC, LLC (US) 1999-06-22 US disclosed
US-5888700-A NONFOGGING, SHELF LIFE KODAK POLYCHROME GRPAHICS, LLC (US) 1999-03-30 US disclosed
US-5821030-A DIRECT DIGITAL EXPOSURE; HIGH WRITING SPEED; ADHESION; ANTIFOGGING AGENTS; SHELF LIFE; USING A POLYCARBOXYLIC ACID IN THE PHOTOPOLYMERIZATION INITIATOR SYSTEM AND A BASIC COMPOUND IN THE OXYGEN BARRIER LAYER KODAK POLYCHROME GRAPHICS (US) 1998-10-13 US disclosed
US-5776655-A CONTAINING PHOTOPOLYMER EASTMAN KODAK COMPANY (US) 1998-07-07 US disclosed
EP-0795790-A2 Peel-developable lithographic printing plate EASTMAN KODAK COMPANY (US) 1997-09-17 EP disclosed
US-5629354-A Photopolymerization initiator system comprising a spectral sensitizer and a polycarboxylic acid co-initiator EASTMAN KODAK COMPANY (US) 1997-05-13 US disclosed
EP-0730201-A1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates EASTMAN KODAK COMPANY (US) 1996-09-04 EP disclosed
EP-0276016-B1 PHOTOPOLYMERIZABLE COMPOSITION Nippon Paint Co., Ltd. (JP) 1992-08-12 EP disclosed
US-4965171-A POLYMERIZABLE, ETHYLENICALLY UNSATURATED COMPONENT WITH PHOTOINITIATOR OF COUMARIN DYE, DIARYLIODONIUM SALT AND AMINE OR THIOPHENOXYACETIC ACID NIPPON PAINT CO., LTD. (JP) 1990-10-23 US disclosed
US-4950581-A HIGH PHOTOSENSITIVITY; USING PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US disclosed
US-4948694-A CONTAINING PHOTOINITIATOR COMPRISING CAMPHORQUINONE AND COUMARIN DERIVATIVE; SENSITIVITY, STORAGE STABILITY CANON KABUSHIKI KAISHA (JP) 1990-08-14 US disclosed
US-4868092-A SENSITIVE TO VISIBLE LIGHT, XANTHENE DYE INITIATOR NIPPON PAINT CO., LTD. (JP) 1989-09-19 US disclosed
US-4152159-A ACRYLIC ESTER POLYMERS EASTMAN KODAK COMPANY (US) 1979-05-01 US disclosed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US disclosed