SCHEMBL6836388

SCHEMBL6836388

COc1ccc2cc(C(=O)c3cc4c(OC)cc(OC)cc4oc3=O)c(=O)oc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
KDM4E B2RXH2 5/20 0.65
RAB9A P51151 3/20 0.65
NPC1 O15118 3/20 0.65
POLB P06746 2/20 0.65
MAOB P27338 5/20 0.64
HPGD P15428 4/20 0.64
GAA P10253 3/20 0.64
SLC16A3 O15427 1/20 0.64
CYP2C19 P33261 1/20 0.61
GLA P06280 2/20 0.60
HSD17B10 Q99714 2/20 0.60
CA12 O43570 1/20 0.58
CA2 P00918 1/20 0.58
CA3 P07451 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5940595 0.92 MEN1 (0.56) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL6836396 0.92 KDM4E (0.63) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL556704 0.90 ALDH1A1 (0.55) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL29436270 0.90 ALDH1A1 (0.55) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL4567092 0.89 NPC1 (0.59) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL52650 0.88 ALDH1A1 (0.81) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL9643088 0.87 CYP2C19 (0.58) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL29811188 0.86 MAOB (0.60) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL4451904 0.86 MAOB (0.60) ALDH1A1KDM4ERAB9ANPC1POLB
SCHEMBL2992219 0.85 MEN1 (0.59) ALDH1A1KDM4ERAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
US-20040198859-A1 Photopolymerization systems and their use NGUYEN CHAU K (US) 2004-10-07 US disclosed
EP-0795790-B1 Peel-developable lithographic printing plate KODAK POLYCHROME GRAPHICS LLC (US) 2002-09-25 EP disclosed
EP-0730201-B1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2001-05-09 EP disclosed
US-5942372-A COMPRISED A SPECTRAL SENSITIZER THAT SENSITIZES IN THE ULTRAVIOLET OR VISIBLE REGIONS OF THE SPECTRUM AND AN N-ARYL POLYCARBOXYLIC ACID CO-INITIATOR; VERY HIGH PHOTOSPEED AND VERY GOOD SHELF-LIFE IN COMPUTER-TO-PLATE SYSTEMS KODAK POLYCHROME GRAPHICS, LLC (US) 1999-08-24 US disclosed
US-5914215-A ELEMENT COMPRISING SUPPORT HAVING PHOTOIMAGEABLE, RADIATION SENSITIVE LAYER COMPRISING UNSATURATED COMPOUND, PHOTOINITIATOR SYSTEM COMPRISING SENSITIZER SENSITIZING IN ULTRAVIOLET OR VISIBLE REGION OF SPECTRUM, CO-INITIATOR KODAK POLYCHROME GRAPHIC, LLC (US) 1999-06-22 US disclosed
US-5888700-A NONFOGGING, SHELF LIFE KODAK POLYCHROME GRPAHICS, LLC (US) 1999-03-30 US disclosed
US-5821030-A DIRECT DIGITAL EXPOSURE; HIGH WRITING SPEED; ADHESION; ANTIFOGGING AGENTS; SHELF LIFE; USING A POLYCARBOXYLIC ACID IN THE PHOTOPOLYMERIZATION INITIATOR SYSTEM AND A BASIC COMPOUND IN THE OXYGEN BARRIER LAYER KODAK POLYCHROME GRAPHICS (US) 1998-10-13 US disclosed
US-5776655-A CONTAINING PHOTOPOLYMER EASTMAN KODAK COMPANY (US) 1998-07-07 US disclosed
EP-0795790-A2 Peel-developable lithographic printing plate EASTMAN KODAK COMPANY (US) 1997-09-17 EP disclosed
US-5629354-A Photopolymerization initiator system comprising a spectral sensitizer and a polycarboxylic acid co-initiator EASTMAN KODAK COMPANY (US) 1997-05-13 US disclosed
EP-0730201-A1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates EASTMAN KODAK COMPANY (US) 1996-09-04 EP disclosed
US-4992351-A Recording medium having a specified photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1991-02-12 US disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US disclosed