Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.45 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683696 | 0.89 | HTR2A (0.48) | HTR2AMAPK1ADORA2BGLABLM | |
| SCHEMBL684065 | 0.88 | HTR2A (0.52) | HTR2AMAPK1ADORA2BGLABLM | |
| SCHEMBL684023 | 0.84 | HTR2A (0.58) | HTR2AMAPK1ADORA2BGLABLM | |
| SCHEMBL684026 | 0.84 | MAPK1 (0.49) | HTR2AMAPK1ADORA2BGLABLM | |
| SCHEMBL682830 | 0.83 | ADORA2B (0.50) | HTR2AADORA2BGLABLMTNF | |
| SCHEMBL683665 | 0.83 | ADORA2B (0.47) | HTR2AMAPK1ADORA2BGLABLM | |
| SCHEMBL683652 | 0.82 | MAPK1 (0.55) | HTR2AMAPK1GLATNFUSP2 | |
| SCHEMBL682828 | 0.82 | ADORA2B (0.46) | HTR2AMAPK1ADORA2BGLABLM | |
| SCHEMBL684376 | 0.82 | ADORA2B (0.46) | HTR2AMAPK1ADORA2BGLABLM | |
| SCHEMBL684062 | 0.82 | HTR2A (0.52) | HTR2AMAPK1ADORA2BGLABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | HTR2A 1201/4885MAPK1 470/4885ADORA2B 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.