Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9313034 | 0.98 | CXCR2 (0.45) | CXCR2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL9749743 | 0.84 | CXCR2 (0.51) | CXCR2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL28608254 | 0.79 | CYP1A2 (0.51) | CXCR2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL28515684 | 0.78 | KMT2A (0.57) | CXCR2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL6836389 | 0.77 | CXCR2 (0.63) | CXCR2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL11579609 | 0.76 | TRPA1 (0.41) | CXCR2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL11211267 | 0.76 | CYP3A4 (0.50) | CXCR2GAAKMT2AALDH1A1KDM4E | |
| SCHEMBL24714329 | 0.76 | MAPT (0.57) | GAAKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL6836192 | 0.76 | GAA (0.60) | CXCR2GAAKMT2AMEN1LMNA | |
| SCHEMBL6226347 | 0.74 | KDM1A (0.49) | GAAKMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6752839-B1 | 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES | L'OREAL (FR) | 2004-06-22 | — | — | US | claimed |
| US-6530960-B1 | Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades | L'OREAL S.A. (FR) | 2003-03-11 | — | — | US | claimed |
| EP-1093788-A1 | Oxydative dyeing composition for keratinic fibres and dyeing process using this composition | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093792-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using the same | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093793-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093791-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093789-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using the same | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093790-A2 | Oxydative dyeing composition for keratinic fibres and dyeing process using this composition | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| US-6752839-B1 | 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES | L'OREAL (FR) | 2004-06-22 | — | — | US | disclosed |
| US-6530960-B1 | Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades | L'OREAL S.A. (FR) | 2003-03-11 | — | — | US | disclosed |
| EP-1093788-A1 | Oxydative dyeing composition for keratinic fibres and dyeing process using this composition | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093792-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using the same | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093789-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using the same | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093791-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093793-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093790-A2 | Oxydative dyeing composition for keratinic fibres and dyeing process using this composition | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |