SCHEMBL6836192

SCHEMBL6836192

Cc1ccc(NC(=O)CCC(N)=O)c(O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.60
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
KMT2A Q03164 5/20 0.53
MEN1 O00255 3/20 0.53
LMNA P02545 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TP53 P04637 1/20 0.51
THRB P10828 1/20 0.51
PARP1 P09874 1/20 0.51
CXCR2 P25025 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
HSD17B10 Q99714 1/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28515684 0.87 KMT2A (0.57) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6835468 0.86 GAA (0.61) GAANPC1RAB9AKMT2AMEN1
Hydrochloric Acid SCHEMBL9313818 0.84 GAA (0.60) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6836397 0.84 GAA (0.59) GAANPC1RAB9AKMT2AMEN1
SCHEMBL7764411 0.82 KMT2A (0.54) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6836552 0.80 KMT2A (0.61) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6838424 0.80 LMNA (0.56) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6836390 0.80 NPC1 (0.62) GAANPC1RAB9AKMT2AMEN1
SCHEMBL7719074 0.80 GAA (0.76) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6836389 0.80 CXCR2 (0.63) GAANPC1RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US claimed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US claimed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093792-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US disclosed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US disclosed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093792-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP disclosed
US-5334225-A Imparts color tone of high chroma; excellent in coloring power and fastness KAO CORPORATION (JP) 1994-08-02 US disclosed
EP-0579204-A2 Dye composition for a keratinous fiber KAO CORPORATION (JP) 1994-01-19 EP disclosed