SCHEMBL562113

SCHEMBL562113

CCOC(=O)C(CCCNC(=N)N)NC(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.47
ACHE P22303 2/20 0.47
CYP26A1 O43174 1/20 0.46
PADI1 Q9ULC6 4/20 0.46
PADI4 Q9UM07 4/20 0.46
PDE4A P27815 3/20 0.46
PADI2 Q9Y2J8 3/20 0.46
PADI3 Q9ULW8 3/20 0.46
PDE4B Q07343 2/20 0.46
PDE4C Q08493 2/20 0.46
PDE4D Q08499 2/20 0.46
PADI6 Q6TGC4 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
NAAA Q02083 1/20 0.42
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
CTSL P07711 1/20 0.41
P2RY12 Q9H244 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80453 1.00 BCHE (0.47) BCHEACHECYP26A1PADI1PADI4
SCHEMBL15739025 0.99 BCHE (0.46) BCHEACHECYP26A1PADI1PADI4
Hydrochloric Acid SCHEMBL538996 0.99 BCHE (0.46) BCHEACHECYP26A1PADI1PADI4
Hydrochloric Acid SCHEMBL11325263 0.99 BCHE (0.46) BCHEACHECYP26A1PADI1PADI4
SCHEMBL1396385 0.91 BCHE (0.48) BCHEACHECYP26A1PADI1PADI4
SCHEMBL15271466 0.91 BCHE (0.48) BCHEACHECYP26A1PADI1PADI4
SCHEMBL158087 0.91 CA1 (0.54) CYP26A1PADI1PADI4PDE4APADI2
SCHEMBL31206858 0.91 CA1 (0.54) CYP26A1PADI1PADI4PDE4APADI2
SCHEMBL16289858 0.91 CA1 (0.54) CYP26A1PADI1PADI4PDE4APADI2
Hydrochloric Acid SCHEMBL29401063 0.89 CA1 (0.53) CYP26A1PADI1PADI4PDE4APADI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4222255-A1 METHOD FOR PRODUCING BETA-TRYPSIN Ipsen Biopharm Limited (GB) 2023-08-09 EP claimed
EP-3219335-B1 COATING COMPOSITION AND MEDICAL DEVICE TERUMO CORP (JP) 2018-12-19 EP claimed
CN-105211672-B A kind of hypersensitive method of reduction river crab meat 江苏省农业科学院 2018-11-02 CN claimed
EP-3219335-A1 COATING COMPOSITION AND MEDICAL DEVICE Terumo Kabushiki Kaisha (JP) 2017-09-20 EP claimed
US-20170143663-A1 COATING COMPOSITION AND MEDICAL DEVICE TERUMO KABUSHIKI KAISHA (JP) 2017-05-25 US claimed
EP-2813250-B1 COATING COMPOSITION AND MEDICAL DEVICE TERUMO CORP (JP) 2017-05-03 EP claimed
CN-104203297-B Coating composition and medical device TERUMO CORP. (JP) 2016-04-06 CN claimed
US-20150056265-A1 COATING COMPOSITION AND MEDICAL DEVICE TERUMO KABUSHIKI KAISHA (JP) 2015-02-26 US claimed
EP-2813250-A1 COATING COMPOSITION AND MEDICAL DEVICE Terumo Kabushiki Kaisha (JP) 2014-12-17 EP claimed
US-20120178114-A1 METHODS AND DEVICES FOR DETECTING THROMBIN GENERATION SUBC, INC. (US) 2012-07-12 US claimed
WO-2009023538-A1 METHODS AND DEVICES FOR DETECTING THROMBIN GENERATION MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2009-02-19 WO claimed
US-12559570-B2 Anti-PAD2 antibody PHARMA FOODS INTERNATIONAL CO., LTD. (JP) 2026-02-24 US disclosed
US-20250236683-A1 COMPOSITION AND METHOD FOR INHIBITING FIBROSIS PHARMA FOODS INTERNATIONAL CO., LTD. (JP) 2025-07-24 US disclosed
EP-4501354-A1 COMPOSITION AND METHOD FOR INHIBITING FIBROSIS Pharma Foods International Co., Ltd. (JP) 2025-02-05 EP disclosed
US-20240309112-A1 NOVEL ANTI-PAD4 ANTIBODY MITSUBISHI TANABE PHARMA CORPORATION (JP) 2024-09-19 US disclosed
US-4234477-A DIAGNOSTIC DETERMINATION OF A HYDROLASE, CALLICREIN BAYER AKTIENGESELLSCHAFT (DE) 1980-11-18 US disclosed
US-4138292-A ENZYMES OR MICROORGANISMS IN A SULFATED POLYSACCHARIDE GEL TANABE SEIYAKU CO., LTD. (JP) 1979-02-06 US disclosed
US-4014860-A Plasminostreptin (enzyme inhibitor) and method for producing it from streptomyces TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-03-29 US disclosed
US-3983001-A Isolation of biologically active compounds by affinity chromatography CESKOSLOVENSKA AKADEMIE VED (CS) 1976-09-28 US disclosed
US-3959080-A Carrier matrix for the fixation of biochemically effective substances and process for the preparation thereof MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559570-B2 Anti-PAD2 antibody PADI2, PADI1, PADI4 BCHE 2229/4885ACHE 3055/4885CYP26A1 1876/4885
US-20170143663-A1 COATING COMPOSITION AND MEDICAL DEVICE SLC6A19, SLC7A1, SLC38A7 BCHE 746/4885ACHE 3037/4885CYP26A1 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.