Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670198 | 0.87 | MAOB (0.61) | KDM4EMAOAMAOBGRM5S100A4 | |
| SCHEMBL6293635 | 0.87 | ALDH1A1 (0.51) | MAOAMAOBGRM5NPC1RAB9A | |
| SCHEMBL2972261 | 0.84 | TSHR (0.60) | MAOAMAOBGRM5NPC1RAB9A | |
| SCHEMBL32670189 | 0.84 | MAOB (0.47) | KDM4EMAOAMAOBGRM5NPC1 | |
| SCHEMBL32670081 | 0.84 | MAOB (0.47) | KDM4EMAOAMAOBGRM5NPC1 | |
| SCHEMBL18157490 | 0.83 | KDM4E (0.50) | KDM4ES100A4NPC1RAB9AMAPT | |
| SCHEMBL29446216 | 0.83 | GRM5 (0.47) | KDM4EMAOAMAOBGRM5NPC1 | |
| SCHEMBL670311 | 0.83 | GRM5 (0.47) | KDM4EMAOAMAOBGRM5NPC1 | |
| SCHEMBL12316616 | 0.80 | CYP1A2 (0.63) | KDM4EMAOAMAOBNPC1RAB9A | |
| SCHEMBL6832861 | 0.80 | NPC1 (0.60) | MAOAMAOBGRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035380-A1 | INHIBITION OF GLIAL CELL ACTIVATION | LAPKO INC DBA AFECTA PHARMACEUTICALS (US) | 2026-02-05 | — | — | US | disclosed |
| US-8742110-B2 | Spiroxazolidinone compounds | MERCK SHARP & DOHME CORP. (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130131042-A1 | SPIROXAZOLIDINONE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | US | disclosed |
| US-6756432-B2 | POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-06-29 | — | — | US | disclosed |
| US-20030153655-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035380-A1 | INHIBITION OF GLIAL CELL ACTIVATION | CHAT, CCRL2, PMP22 | KDM4E 4249/4885MAOA 1198/4885MAOB 1170/4885 |
| US-20130131042-A1 | SPIROXAZOLIDINONE COMPOUNDS | SSTR5, SSTR2, SSTR4 | KDM4E 4514/4885MAOA 968/4885MAOB 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.