Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 6/20 | 0.66 |
| ▸ | DRD2 | P14416 | 5/20 | 0.66 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837827 | 0.81 | RXFP1 (0.68) | RXFP1KDM4EHSD17B10KMT2ACYP2C9 | |
| SCHEMBL6836700 | 0.80 | RXFP1 (0.67) | RXFP1KDM4EHSD17B10KMT2ACYP2C9 | |
| SCHEMBL6399889 | 0.80 | CCR3 (0.65) | RXFP1DRD3DRD2DRD4HDAC1 | |
| SCHEMBL29233597 | 0.79 | CYP1A2 (0.70) | RXFP1DRD3KDM4EHSD17B10KMT2A | |
| SCHEMBL6837571 | 0.78 | KMT2A (0.76) | RXFP1DRD3DRD2HDAC1HDAC2 | |
| SCHEMBL6839390 | 0.78 | RXFP1 (0.63) | RXFP1KDM4EHSD17B10KMT2ALMNA | |
| SCHEMBL29530276 | 0.78 | LMNA (0.73) | RXFP1DRD2DRD4KDM4EHSD17B10 | |
| SCHEMBL6839495 | 0.76 | HDAC1 (0.69) | RXFP1DRD3DRD2DRD4HDAC1 | |
| SCHEMBL5584871 | 0.76 | KMT2A (0.72) | RXFP1HDAC1HDAC2KDM4EHSD17B10 | |
| SCHEMBL6837896 | 0.75 | KMT2A (0.63) | RXFP1HDAC1HDAC2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716987-B1 | PHOSPHODIESTERASE IV INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020128290-A1 | DERIVATIVES OF BENZOFURAN OR BENZODIOXOLE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128290-A1 | DERIVATIVES OF BENZOFURAN OR BENZODIOXOLE | CBR1, CBR3, CYC1 | RXFP1 1019/4885DRD3 334/4885DRD2 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.