Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | BMP1 | P13497 | 2/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837571 | 0.88 | KMT2A (0.76) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6839495 | 0.86 | HDAC1 (0.69) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31530557 | 0.84 | ADORA2A (0.61) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5584871 | 0.83 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL978037 | 0.82 | LMNA (0.77) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6833294 | 0.82 | RAB9A (0.66) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10664760 | 0.82 | MAPT (0.56) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5584565 | 0.81 | RAB9A (0.72) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6839243 | 0.80 | NPC1 (0.74) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7367818 | 0.79 | LMNA (0.68) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716987-B1 | PHOSPHODIESTERASE IV INHIBITORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-04-06 | — | — | US | disclosed |
| US-6514996-B2 | Derivatives of benzofuran or benzodioxole | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-02-04 | — | — | US | disclosed |