SCHEMBL6837636

SCHEMBL6837636

OC[C@H]1OC(O)[C@@](O)(F)[C@@H](O)[C@@H]1O

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 2/20 0.36
LGALS3 P17931 2/20 0.36
LGALS9 O00182 1/20 0.36
LGALS8 O00214 1/20 0.36
PYGB P11216 4/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
OGA O60502 5/20 0.33
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC5A2 P31639 1/20 0.33
HEXB P07686 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17610102 1.00 LGALS1 (0.36) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL6837637 1.00 LGALS1 (0.36) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL27818667 1.00 LGALS1 (0.36) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL2236561 0.87 CDA (0.35) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL8857040 0.87 CDA (0.35) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL8857031 0.87 CDA (0.35) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL18789291 0.87 CDA (0.35) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL967650 0.81 LGALS1 (0.38) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL10344684 0.81 LGALS1 (0.38) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL25432185 0.78 LGALS1 (0.39) LGALS1LGALS3LGALS9LGALS8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116411353-A Synthesis method of DNA coding compound oxo-glycoside 成都先导药物开发股份有限公司 2023-07-11 CN claimed
EP-2260101-B1 MICRORNA (MIRNA) MIR-21 FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES UNIV WUERZBURG J MAXIMILIANS (DE) 2013-05-29 EP claimed
CN-116411353-A Synthesis method of DNA coding compound oxo-glycoside 成都先导药物开发股份有限公司 2023-07-11 CN disclosed
CN-113264967-B Programmed death ligand-1 targeted compound and preparation method and application thereof 江苏省原子医学研究所 2023-04-18 CN disclosed
CN-1240380-C Phase transfer catalyzed glycosidation of indolopyrrolocarbazoles MERCK & CO INC (US) 2006-02-08 CN disclosed
CN-1482908-A Phase transfer catalyzed glycosidation of an indolocarbazole 2004-03-17 CN disclosed
US-20040024196-A1 Phase transfer catalyzed glycosidation of an indolocarbazole PETRILLO DANIEL E (US) 2004-02-05 US disclosed
EP-1333826-A2 PHASE TRANSFER CATALYZED GLYCOSIDATION OF AN INDOLOCARBAZOLE Merck & Co., Inc. (US) 2003-08-13 EP disclosed
US-6555677-B2 Preparing preferential compound; incubate sugar with activating agent, couple activated sugar with preferential compound, recover compound MERCK & CO., INC. 2003-04-29 US disclosed
US-20020058803-A1 Phase transfer catalyzed glycosidation of an indolocarbazole BANYU PHARMACEUTICAL CO., LTD. (JP) 2002-05-16 US disclosed
WO-2002036601-A2 PHASE TRANSFER CATALYZED GLYCOSIDATION OF AN INDOLOCARBAZOLE MERCK & CO., INC. (US) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024196-A1 Phase transfer catalyzed glycosidation of an indolocarbazole UGGT1, UGCG, GPI LGALS1 802/4885LGALS3 362/4885LGALS9 1065/4885
US-20020058803-A1 Phase transfer catalyzed glycosidation of an indolocarbazole UGGT1, UGCG, GPI LGALS1 802/4885LGALS3 362/4885LGALS9 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.