SCHEMBL6838356

SCHEMBL6838356

CCN1CCNCC1(CC)CC

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
SOS1 Q07889 1/20 0.32
SOS2 Q07890 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL510056 0.80 SOS1 (0.32) SOS1SOS2
SCHEMBL4893037 0.79 GNAI3 (0.35) TSHR
SCHEMBL28153211 0.79 GNAO1 (0.36) SOS1SOS2
SCHEMBL25263941 0.77 TSHR (0.34) TSHRSOS1SOS2
SCHEMBL9801465 0.76 TSHR (0.36) TSHRSOS1SOS2
SCHEMBL28142685 0.76 SOS1 (0.47) TSHRSOS1SOS2
SCHEMBL7026604 0.76 SOS1 (0.33) TSHRSOS1SOS2
SCHEMBL8655459 0.75 TSHR (0.33) TSHRSOS1SOS2
SCHEMBL7026605 0.75 TSHR (0.33) TSHRSOS1SOS2
Bromide SCHEMBL6291796 0.75 GNAO1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111246873-B Optimized peptides for targeting human nerves and their use in image guided surgery, diagnosis and therapy delivery 加利福尼亚大学董事会 2024-03-01 CN disclosed
WO-2022071027-A1 METHOD FOR TREATING WASTEWATER CONTAINING ORGANIC SUBSTANCE 日東電工株式会社 2022-04-07 WO disclosed
WO-2021117631-A1 COMPOSITE SEMI-PERMEABLE MEMBRANE 日東電工株式会社 2021-06-17 WO disclosed
CN-111246873-A Optimized peptides for targeting human nerves and their use in image-guided surgery, diagnosis and therapy delivery 加利福尼亚大学董事会 2020-06-05 CN disclosed
EP-0992537-B1 Oil extended rubber and rubber composition JSR CORP (JP) 2004-12-29 EP disclosed
US-6362272-B1 CONJUGATED DIOLEFIN AND AROMATIC VINYL COPOLYMER JSR CORPORATION (JP) 2002-03-26 US disclosed
EP-0992537-A1 Oil extended rubber and rubber composition JSR Corporation (JP) 2000-04-12 EP disclosed